Four colon polypoid adenomas stained positively throughout, but 6/10 primary tumours had partial or complete loss of expression of monomorphic determinants using mAb W6/32: two node and the liver metastasis showed less, four more expression.
In-DOTA-CCK showed some activity in the liver, In-DOTA-MG11 showed less liver activity and with 99mTc-demogastrin 2 the liver was hardly visible.
After day 4 p.i., the livers from mice examined showed less severe hepatocellular damage than livers taken earlier, and the livers examined on day 6 p.i. showed near complete resolution.
In a mammalian study, homozygous CYP1A1 knockout mice showed less liver damage and survived the acute effects of injection of the PAH benzo(a pyrene (BaP) for 3 days longer than did those that were heterozygous for CYP1A1 (Uno et al. 2001).
The heart, liver, spleen, and lungs all showed less ADR accumulation with liposomal ADR treatment than with free ADR treatment.
Although TUNEL-positive nuclei were absent or rare (without intergroup difference) in the heart and the liver, respectively, AVP-treated animals showed less TUNEL-positive renal tubular nuclei (3 (3 to 9) versus 11 (5 to 15), respectively, P = 0.061).
Subsequent challenge with schistosome cercariae produced higher percentages of worm reduction (41.1%, 30.4% and 24.7%, respectively) but showed less efficacy of liver egg reduction (26.6%, 25.6% and 14.4%, respectively) in the first experiment (Table 2, Exp 1).
In some instances, the tumour area showed less uptake than normal liver.
Accordingly, liver sections obtained 8 days after LCMV infection showed less LCMV NP in Ncf1−/− mice.
Ucn3+ mice lost a greater proportion of liver weight (a measure of glycogen mobilisation and depletion) and showed less hepatic glycogen staining after fasting (Fig. 3b, c).
