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In male livers, levels of pS6 were several times higher and statistically significant in comparison to females (Fig. 3A).
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Interestingly, in liver 5' levels of NAIP are the highest (Figure 1c), potentially arising from transcription of 3' deleted isoforms, premature poly-adenylation, or CNV-associated anomaly within the tissue sample screened.
Changes in the liver levels of many metabolites were inconsistent with their levels in plasma.
Endogenous liver levels of PEDF decline in experimental and human cirrhosis, and PEDF delivery ameliorates experimental liver fibrosis.
The significant decrease of liver levels of hypoxanthine, purine and adenosine suggest that exposure to GalN/LPS disrupts nucleotide metabolism.
A multitude of metabolites inside liver cells are released into the blood within a short time, which impacts liver levels of metabolites.
Interestingly, the baseline liver levels of expression of IFN-stimulated genes were higher in non-responderss than in sustained virological responders.
Among the amino acids identified, liver levels of glycine, B-alanine, proline, glutamate and tyrosine decreased and lysine increased significantly in the ALF group.
Results for hair and nail are given in Fig. 6 for a differentiation towards dogs with Cu liver levels of < 600 mg kg−1 or > 600 mg kg−1.
Three hours after feeding, there was no significant difference in plasma or liver levels of MIR168a between mice fed regular chow or raw rice.
The serum and liver levels of MDA, GSH, and CAT activity were comparable in both the CCM and C Groups (p > 0.05).
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