Our territorial model keeps this basic assumption but introduces more partitions to the normal liver based on arterial liver territories, see the "Determination of arterial liver territories" section.
We propose an optimized, extended partition model, called territorial model (TM), introducing more partitions to the normal liver based on arterial liver territories [7].
For the liver, based on a 30% blood volume fraction [18], a liver-to-blood AUC ratio of 0.3 would be expected.
Comparison of isotopes useful for radiolabeling liposomes - estimated absorbed radiation dose in liver, based on mice injected with 64Cu-MM-302.
To develop a local and global function model in the liver based on regional and organ function measurements to support individualized adaptive radiation therapy (RT).
We also provide a successful in vivo delivery of siRNA to the liver based on a newly designed pH-responsive cationic lipid.
However, with the increase in surgical procedures, for example resection and transplant, the need for a more functional description of the liver based on its vascular and biliary architecture evolved.
It can be seen from this Table that in humans, there is good agreement between modelling and Patlak-Rutland analysis [2] and that our mean value of Ki/V 0) for the liver, based on Patlak-Rutland analysis, is similar to previously published values in humans based on both modelling and Patlak-Rutland analysis [1, 2].
The two signal molecules c-JUN and FOXM1B have been suggested as being the factors responsible for HCC development in PB-treated mouse liver based on the fact that the c-Jun−/− and Foxm1b−/− mice exhibited attenuated HCC development [19], [20].
We have developed the SCID/uPA mouse model of human liver, based on transgenic mice in which uPA expression is targeted to hepatocytes (Alb-uPA), and this achievement has advanced our understanding of the in vivo replication properties of Hepatitis C virus[8].
