Moreover, the effects of YKS on liver function were examined.
Plasma activities of circulating enzymes including alanine aminotransferase and aspartate aminotransferase as indicators of liver function were not affected by experimental diets.
The oxidative stress and overall liver function were improved under Co-Q10 therapy as evidenced by significant reduction in oxidative stress markers and preservation of antioxidant factors.
Liver function were disturbed in 2% in patients who received 20 mg or less/kg body weight compared to 4% in those who received a dose of >20 mg/kg 5-ALA.
He did not suffer from liver disease, and laboratory data for liver function were normal.
Imaging and clinical parameters of liver function were tested for association with overall survival.
Image parameters of liver function were tested for association to overall survival with Cox proportional hazard regression.
The improvements in liver function were accompanied by significant improvements in psychometric tests and in degree of encephalopathy.
A recent meta-analysis evaluated 5 randomized, double blind and controlled studies in all of which no adverse effects on liver function were reported [66].
Laboratory data on liver function were nearly normal, and the levels of tumor markers such as alpha-fetoprotein, prothrombin induced by vitamin K absence or antagonist II, carcinoembryonic antigen, and carbohydrate antigen 19-9 were also normal.
The biochemical markers used to assess liver function were ALT and AST which are the most sensible biomarkers promptly involved in the extent of hepatocellular injury (Chun, Tong, Busuttil, & Hiatt, 2009; Singh, Bhat, & Sharma, 2011) and their increase in serum is a marker of cellular outflow and lack of the functional integrity of cell membranes of hepatocytes (Rajesh & Latha, 2004).
