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In advanced forms of the disease, the infiltration of organs by the mast cells leads to low blood counts and liver function abnormalities as well as malabsorption and weight loss.
Laboratory tests showed a severe inflammatory reaction and mild liver function abnormalities.
The prevalence of liver function abnormalities ranges from 20 to 80%% [3, 4], and a few reports have described severe consequences of the liver involvement [5].
Previous hepatic damage from viral hepatitis and liver function abnormalities existing at the time of grafting do not appear to increase the risk of posttransplant morbidity and mortality from hepatocellular damage or venocclusive disease in cyclophosphamide-conditioned patients.
They were negative for arterial hypertension, proteinuria, liver function abnormalities, peripheral edema on examination; moreover, none of the drugs used in the peripartum period could be responsible for PRES.
Furthermore, a negative eclampsia panel ruled out eclampsia, as well as there was no evidence of arterial hypertension, proteinuria, liver function abnormalities or peripheral edema on examination and none of the drugs used in the peri-partum period had a vasoactive effect which could have been responsible for RCVS.
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Recently, Tripathi et al. [23] demonstrated that liver function abnormality is caused by elevated serum ALT, AST, ALP and bilirubin.
The incidence of liver function abnormality increases approximately 4- to 5-fold with increasing dose of simvastatin [11].
Seven patients had pretreatment grade 1 liver function abnormality.
Liver function abnormality was another major adverse effect.
We speculated whether the generous inclusion criteria for liver function abnormality were responsible for the increased risk of neutropaenic fever.
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