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TAA induced significant increase of MDA and decreased in GSH and NO in both liver and brain homogenate with more liver affection, and increased in serum levels of AST, ALT, triglyceride, cholesterol and decreased in total protein.
Again others present with polyneuropathy, gastrointestinal disturbances, liver affection and so on [6].
None of the children with abnormal TE or ELF test results had abnormal transaminases, meaning that ELF and TE were the only parameters indicating liver affection.
Available results of genetic testing and family history data regarding cystic kidney disease as well as potential liver affection are included.
Liver function tests and other routine laboratory data (including viral markers and autoantibodies) were performed using standard methods to evaluate the degree of liver affection as well as to identify/exclude any associated hepatic condition.
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Although there is no evidence for serious liver affections or failure provoked by TOZ, organ function should also be evaluated at regular intervals due to the frequency of slight and often transient increases in aminotransferases [ 69].
The reduction of blood cells observed in the treated animals could be ascribed to oil toxicity linked to bone marrow failure [ 45] or liver and spleen affection [ 21].
Side effects include dyspepsia, hand tremors, weight increase, affection of the liver, thrombocytopaenia and foetal malformations; see Table 7.
Bilateral lobar affection of the liver was present in 8 patients (34.8%).
The patients excluded from our study were; patients with cardiac disease, patients with renal affection, and patients with liver diseases (drug induced, autoimmune disease and viral hepatitis).
In addition, the genes derived from the OPLS-DA analysis for classification purposes enabled the creation of a model that could accurately predict the affection status of all the liver samples.
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