Sentence examples for little sequence conservation from inspiring English sources

A comparison of the decapeptide sequences from a variety of cytoplasmic Hsp90s suggests that there is very little sequence conservation upstream of the conserved MEEVD motif, except at the −6 position (91% conservation) and −5 position (68% conservation) [ 29].

Accordingly, we examined the MglB sequences that are coupled to Groups 2 5 MglA members to determine whether they contain a conserved residue that could act as a transition state stabilizer similarly to the extrinsic arginine finger of eukaryotic GAPs, but we found very little sequence conservation other than a conserved aspartate glycine pair (fig. 2 C).

Although the SECIS structure is conserved, there is little sequence conservation beyond the consecutive non-Watson-Crick base pairs UGAN/KGAW constituting the quartet, an unpaired A 5 to UGAN and a run of As in the apical loop/internal loop 2 (Fagegaltier et al., 2000; Walczak et al., 1996).

With the exception of a highly conserved Gxxx[T/S] motif (12 ) that in some picornaviruses permits myristoylation, little sequence conservation occurs in the VP0 of THV with respect to other picornaviruses.

However, we found little sequence conservation of Cry6Aa in our functional study.

As noted above, there is surprisingly little sequence conservation between the murine and human NXNL1 upstream regions.

It was later found that an important tertiary interaction between loops on the helices is phylogenetically conserved, albeit with little primary sequence conservation between organisms.

With so little absolute sequence conservation, we next assessed the degree to which residues varied while retaining their chemical property.

The presence of megabase spanning satellite repeats is a hallmark of centromeres, although there is little detectable sequence conservation.

Remarkably, structural elements are preserved in viral Bcl-2 proteins even though there is in many cases little discernible sequence conservation with their mammalian counterparts.

Group I and group II introns show little primary sequence conservation, yet their RNAs each adopt characteristic secondary and tertiary structures necessary for ribozyme activity [ 13, 14].