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We show that the treatments that spread are not necessarily those that are most efficacious at curing the ailment, and explain how 'superstitious treatments' with little efficacy and even maladaptive practices can spread under broad conditions.
Behavioural interventions alone have shown little efficacy, indicating limited success in modulating neuroplasticity, especially in brains with neural atypicalities.
(Sweet cherries, by the way, have shown little efficacy in exercise-related experiments).
Little efficacy as scab protectants was demonstrated when each SIR product and penconazole was applied at only two growth stages (bud break, green cluster).
A two-stage design that allows for early termination of the trial if the treatment shows little efficacy such as Gehan or Simon gives equal weight to a CR and a PR.
Less frequent drug administration was better tolerated (dose-limiting toxicity was myelosuppression), but little efficacy was observed.
Similar(11)
β-blockers were found to exert little antitumour efficacy when used alone, but increased treatment efficacy and prolonged median survival when used in combination with vincristine, through antimitochondrial and anti-angiogenic mechanisms.
The free curcumin showed little anticancer efficacy due to its quite limited solubility.
By contrast, IL-12 has shown little therapeutic efficacy in EOC in two clinical trials [57], [58].
Free doxorubicin exhibited little therapeutic efficacy at this concentration, as the tumor size in this group was only 16% smaller than that in the PBS group (Fig. 3A).
Increasing dose to 45 mg/day provides little more efficacy and substantially increases risk of side effects (70).
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