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This conservation is particularly surprising as there is little conserved microsynteny between these species [ 31, 66, 67] and thus may indicate that the function of these miRNAs and their host genes are linked.
The duplicate region experienced fractionation during evolution leading to Brassicaceae and Solanaceae lineages, resulting in scattered bCRK-I orthologs with little conserved synteny, whereas in grasses the tandem duplicate region was lost.
However, the tephritid stripe 2 enhancer and stripe 3 enhancers are 5 kb apart, with little conserved sequence between them.
We choose to include closely related sequences, because phosphorylation sites tend to be little conserved, especially in disordered regions.
Subdomain X is overall little conserved and Ser that was phosphorylated in PSKR1 was present at this position only in that receptor.
That said, ribosomal profiling holds promise as a technology for improving this annotation (Guttman et al. 2013; Ingolia et al. 2014), both by excluding genes, as done here, and also through discovering new ones too short and too little conserved to be annotated by other means (Wilson and Masel 2011; Smith et al. 2014).
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We previously reported that there was little synteny conserved between M. oryzae and the closely related Neurospora crassa, suggesting that the genome of M. oryzae may be highly plastic (Dean et al. 2005).
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Many observers contend the federal program lags behind those in Western Europe and does little to conserve living populations of imperiled breeds, leaving that effort to groups like the livestock conservancy, individuals and universities that maintain animals for research.
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