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Although apoptosis is postulated to play an important role in the pathophysiology of septic cardiomyopathy [5,6], post-mortem studies have demonstrated relatively little cell death, even in cases of undoubted severe septic cardiomyopathy [7,8].
Limiting dilution analysis directly showed that in the presence of IL7, very little cell death occurred in both caspase-3hi and caspase-3low CD8+ T cells.
IHC for cleavage of caspase 3 and histological analysis of the endothelial cells before and after HDIT/HCT showed very little cell death (p = 1, Table 3F).
In the latter case, this parameter was explicitly neglected in the derivation of the growth rate, because earlier viral yield experiments have shown little cell death prior to the peak of the virus concentration (see, e.g., [38], [39]).
Prior to treatment for 24 hours, little cell death was observed in these tumor cells.
Interestingly, infected DC exhibited relatively little cell death over 6 days of infection.
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Either too much or too little programmed cell death seems to be implicated in up to 70percentt of human diseases, Dr. Reed said.
Her mice, she argues, better mimic Alzheimer's disease than do mice that are genetically engineered to have amyloid gunking up their brains; those mice tend to have little brain cell death.
Nucleofection in combination with optimised cell line-specific protocols (Amaxa) yielded highest efficiencies (20 30%) with very little spontaneous cell death (data not shown).
Thereafter, the cultures stabilized and could be propagated with little additional cell death.
While 3 μM cisplatin for 48 h showed typically little effect, cell death was observed with 10 μM cisplatin in many CRC lines, so this dose was used for further drug combination studies.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com