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Although a substantial proportion of candidate gene studies of common variants have failed to replicate, a number of variants have been associated with the risk for CRC (Houlston and Tomlinson 2001; de Jong et al. 2002; Chapelle 2004; Kemp et al. 2004; Sharp and Little 2004; Chen et al. 2005; Little and Sharp 2007).
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It was a little chunky and sharp in spots and there was a hole there about the size of a fist".
Roger Catlin of Hartford Courant wrote that it stands out from other shows on Disney Channel by "being a little sassy and sharp, and a whole lot funnier than most of [the channel's] stuff".
(The album's title, Mr. Longstreth says, symbolizes its juxtapositions of style: "It has something a little bit barbed and sharp, as well as something smooth and affirming and gentle").
But researchers at the University of Iowa found little public data and sharp disparities when they combed past studies evaluating the financial impact of tele-ICUs, said Dr. Gaurav Kumar, the lead author of the review study, published this year in the medical journal Chest.
Harry imagines his grandaughter and how she sees the world with her young eyes, "every little thing vivid and sharp and new, packed full of itself like a satin valentine," but it is Updike who at 58, has the artistry of his long maturity, but still the relentless and greedy eyes of the child.
"Don't the people in here all know you?" They had arrived early, but the place was filling up, with noise and little sharp drafts as the door opened and closed.
Female Paduans, the reporter noticed, look like nothing so much as 18th-century French court ladies, with their bouffant white wigs and sharp little faces.
But her works, cued by Dow's reductivism and her own post-Impressionist leanings, here just manage to hold their own, with simplified forms, rhythmic designs and sharp little touches of Fauve color.
At lunch I sat down across from him and his best friend, Michael Bu, a Chinese boy with a round face and sharp little teeth like a fish.
"You think about the pitch under your feet and little sharp turns are hard to do.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com