Based on the medical history, physical examination, and paraclinical studies, a comparative listing of abnormalities was prepared between the exposed and non-exposed groups.
See supplementary table on bmj.com for a list of congenital abnormalities.
A discussion of the prevalence and prevention of genetic disorders, and a list of genetical abnormalities affecting pregnancies in a consanguineous Muslim society has been described [ 7, 71].
In addition to confirming that studies on mouse embryos can provide insights into human disease, the work of Yu et al. add defects in the cerebellar vermis to the list of developmental abnormalities associated with CHARGE syndrome.
The list of genes associated with 'body fat abnormalities' and brain expression in the mouse may be interesting candidates to consider in future obesity studies.
Autoimmune diseases like lupus, Young continued, could also cause these kinds of abnormalities.
The variety of abnormalities probably have more than one cause, the participants said.
Of 1,900 inflaters tested, none showed signs of abnormalities, Mr. Trowbridge said.
Six of the 10 patients presented in this case series [Patients 1, 2, 4, 8 (on three occasions), 9 and 10] had cranial MRI scans, showing a range of abnormalities; four of six patients (Patients 1, 2, 4 and 9) demonstrated a spectrum of congenital abnormalities listed in detail in Table 1.
However, exposure to a variety of chemical compounds, especially those that have been identified as environmental endocrine disrupters (including mercury, p,p'-DDE, and polychlorinated biphenyls), has elicited all of the listed abnormalities in other species.
