Sentence examples for linked to wild type from inspiring English sources

In addition, we identified phosphorylation sites on adaptor proteins previous linked to wild type FLT3 signaling, such as GAB2, SHP-2, PLCG2, and SHIP1 [32], [33], [34], [35], [35].

Amyloidosis linked to wild type TTR appears to cause senile systemic amyloidosis (SSA) [4], [5], whereas most of the one hundred TTR mutants, already identified, result in familial amyloidotic polyneuropathy (FAP) [6], [7].

In particular, strong HER-2 expression was closely linked to wild-type PTEN (P=0.032).

To investigate whether mutant WT1 proteins interact with p53, HeLa cells that express p53 but no WT1 protein were transfected with plasmids driving expression of GFP, or GFP linked to wild-type WT1, WT1Wilms2 and WT1Wilms3.

However, decreased insulin production and diabetes in Akita mice, which is linked to inadequate wild-type proinsulin delivery to secretory granules [36], may occur before there is any loss of pancreatic beta-cell mass [30].

Co-transfection of pre-miR-27b with the luciferase reporter gene linked to the wild-type 3′-UTR of MSTN strongly inhibited the luciferase activity (79%, p < 0.0001).

Cotransfection of miR-27b with the luciferase reporter gene linked to the wild-type 3′-UTR of PPAR-γ strongly inhibited the luciferase activity, while cotransfection with anti-miR-27b rescued this effect.

We introduced the knockout allele of Otx1 (Acampora et al., 1996) into the Emx1-CreER T2 /MADM system by genetically linking it to the GT cassette through meiotic recombination; in parallel, the TG cassette was linked to the wild-type allele.

These results indicate that organelles not actively transported by motors in p50 overexpressing cells are confined to a larger region than organelles linked to microtubules in wild type cells supporting the fact that MSD⊥ in wild type cells is given by the stiffness of the motor linker.

Female progeny from isofemale lines carrying the X linked transgene (identified by PCR) were crossed to wild type males and their resultant progeny scored for eGFP.

Segregation analysis also suggested that the pax1-1 mutatisn is recessive to wild type and that it is linked to axr3-1 (data not shown).