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A high-throughput sequencing strategy of 12 genes linked to HLH was validated in 13 patients with previously identified HLH-associated mutations and prospectively evaluated in 58 HLH patients.
Although additional analyses are required to validate variants linked to resistance, such finding highlights the necessity to consider both gene expression and polymorphism variations for identifying candidate genes potentially involved in insecticide resistance.
Association analysis between phenotypic variations for cold stress and the SSR markers linked to candidate genes could further validate if these markers are predictive of cold tolerance in oil palm.
We next sought to validate these scaffolds as linked to the grinch locus by meiotic mapping on a panel of mutant embryos.
Popularly known by the moniker "meth mouth," the examples of extreme dental decay and tooth loss were disseminated widely by the news media without being linked to rigorous epidemiological studies that validated the reports.
The test was applied and validated in springs linked to faults with a latent behaviour in Cantabria, Northern Spain.
It appears likely that several genes will also be validated as being linked to RA severity but not to susceptibility.
Our analysis is based on the HIV-1, Human Protein Interaction Database (HHPID), which currently comprises over 2,500 unique interactions, curated from over 3,200 papers with over half of the interactions validated by being linked to multiple publications [ 2, 4].
In a randomly selected sample of 827 patients drawn from a tertiary rheumatology centre (training set), clinically validated diagnoses were linked to administrative data including diagnostic codes and drug prescriptions.
