MM: How is creativity linked to transformation and healing?
Increased OXPHOS has been shown to be important for cell cycle entry and is commonly linked to transformation [24].
We recently reported an acquired loss of renal Dnase1 expression linked to transformation from mild to severe membranoproliferative lupus nephritis in (NZBxNZW F1 mice.
Similarly, T. equi has several homologs of cyclophilins, which have been linked to transformation.
Constitutive NFκB activation is linked to transformation, proliferation, suppression of apoptosis, and metastasis [ 1, 26].
MCF-10A cells have been widely used to study the transforming mechanisms of viral and cellular oncogenes; the mammary epithelial acini-like structures they form in Matrigel-based 3D systems have been helpful to understand how oncogenes deregulate processes linked to transformation, such as proliferation and resistance to apoptosis [ 33, 34].
Several mammalian PcG members have been implicated in the control of cellular proliferation and tumorigenesis (Jacobs and van Lohuizen, 2002), and altered expression of PcG genes is linked to transformation in cell lines and the induction of tumours in mutant mice (Satijn et al, 1997; Satijn and Otte, 1999).
Ms. Stack was even able to link (to Transformations) the Ernst Barlach sculpture titled "The Fighter of the Spirit" (1928), which sits near the institute's front door.
In this review we summarize our current understanding of how 'metabolic transformation' is linked to oncogenic transformation, and why inhibition of metabolism may prove a cancer′s 'Achilles' heel'.
This solidification expansion (SE) could be linked to phase transformations in the alloy.
The enzymes associated with co-metabolism of l-arginine, l-phenyloalanine and putrescine may be linked to ibuprofen transformations.
