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In this case, the difference in CYP6G1 expression levels between the control and resistant samples may have resulted from the selection of cis- or trans-acting regulatory variants linked to the selected E3 allele.
We use a structured-coalescent approach to model the effect of directional selection on the gene genealogies of neutral markers linked to the selected mutant.
During a selective sweep of a favorable allele, any neutral alleles linked to the selected allele will rise in frequency and become overrepresented in the population.
In the second step, primary degrees of freedom are selected by sequential elimination from the candidate degrees of freedom linked to the selected elements through the first step.
Articles providing ICF categories linked to the selected PROMs were used.
However, we found no case of focal GRB7 amplification in HER2- cases suggesting that its activation is linked to the selected advantage conferred by HER2 activation.
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The measures were linked to the previously selected quality indicators (QI), using a modified Delphi Technique with expert panels in each participating country by a team, which was part of the first project [ 22, 23].
Changes in the pattern of neutral variation in the vicinity of a selected site(s) are also informative because, during an adaptive substitution, neutral variants linked to the piece of selected DNA are carried or 'swept' to fixation along with it.
"You may have to learn to play a ground game and to choose a shorter club off the tee," said Bryan Jones, the head of instruction at the David Glenz Golf Academy, which is linked to the Ballyowen Golf Club, consistently selected as one of the best links-style public courses in the New York area.
The economic benefit realized from energy storage units on the electric grid is linked to the control policy selected to govern grid operations.
Finally, the PCR markers were tested on a large segregating population to confirm the genetic linkage between the markers and the gene of interest; and the markers closely linked to the gene were selected and applied in molecular plant breeding.
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