BC's most recent wave of deaths is suspected to be linked to the super-potent opioid carfentanil, which authorities are only beginning to test for.
With increased levels of pain tolerance linked to the release of potent pain-killing chemicals known as endorphins, the test offered scientists an indirect way of gauging changes to endorphin levels in the brain.
The mPGES-1-driven PGE2 signalling on stromal cells may be functionally linked to the induction of potent pro-angiogenic and matrix-degrading factors, which in turn would facilitate tumour development.
As it happens, this observation, made by diagnosticians in the clinic, was eventually linked to the creation of some of the most potent immunological medicines used clinically today.
Notably, in the study by Gustafsson et al. (2013) the local vascular pressure provocation also led to a delayed plasma reduction of vascular endothelial growth factor A (VEGF-A), a potent vasodilator that is linked to the endothelial NO system; NO constitutes a downstream factor in the VEGF-A pathway as well as an upstream activator of VEGF-A expression (Tsurumi et al. 1997; Ziche et al. 1997).
The potent anticancer compound DB-67, a fluorescent camptothecin derivative, was also covalently linked to the polyurethane constructs.
They are potent inhibitors of eukaryotic protein phosphatases 1 and 2A [ 2] and are linked to the deaths of wild animals and livestock worldwide [ 1].
It has been linked to the action of acetaminophen (paracetamol), as the drug possesses weak COX-1 and COX-2 inhibitory effects, but potent antipyretic and analgesic activity.
The reported effect of botulinum toxin upon SP 9 is, we believe, more linked to its potent effect upon dermal and muscular compartments than upon the sebaceous function, as previously suggested.
Siramesine was shown to be a potent inducer of cell death, which was linked to its potent anticancer activity.
