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Remarkably, except for the two amino-acid substitutions, L364D and F380S (haplotypes 4 and 7), which we linked to the functionally distinct HvPHYC alleles, other substitutions were within variable motifs and thus presumably nonfunctional.
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LA is structurally and functionally linked to the left ventricle, functioning as a reservoir during ventricular systole, a conduit during early diastole and contracting during late diastole to aid ventricular filling.
Addition of a further 24 Fe2+ ions resulted in formation of the radical, and we conclude that radical formation is indeed linked to the aromatic residues being functionally important in mineralization.
And since the two known α-subunits of these myocytes do indeed have ouabain sensitivities of about 2 3 orders of magnitude apart [ 18, 27], it is reasonable to conclude that the EGFR-Src/Ras/Raf/ERK cascade is functionally linked to the insensitive α1-isoform, and that the PI3Kα/Akt is functionally linked to the sensitive α2-isoform.
This is in-line with the recent findings that long ncRNAs are functionally linked to the nervous system, neuronal diseases and brain function (Chodroff et al., 2010; Qureshi et al., 2010).
NKCC1 carries Cl - into the cells and is functionally closely linked to the ionotropic GABA receptors (iGABAR's) which function as Cl - -permeable ligand- (GABA-) gated channels.
"It gives further credence to this idea that these spine abnormalities are functionally linked to the behavioral disorders".
IL-10 was evaluated in several studies and functionally linked to the "classical" biphasic response model to severe injury [42, 43].
The mPFC is functionally linked to the limbic system (Vertes [2006]) and anatomically is subdivided into infralimbic (IL), prelimbic (PL), and dorsal anterior cingulate (dAC) (Czeh et al. [2008]).
These findings suggest that relatively large jaw-muscle PCSAs can be added to the suite of masticatory features that have been functionally linked to the exploitation of a more resistant diet by C. apella.
Vitamin D serves as a principal modulator of skeletal gene transcription, thus necessitating an understanding of interfaces between the activity of this steroid hormone and regulatory cascades that are functionally linked to the regulation of skeletal genes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com