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F-actin visualized by phalloidin became dramatically concentrated, corroborating the suggestion that all these changes on the egg surface are linked to the alteration of the cortical actin cytoskeleton in the subplasmalemmal region of the JAS-treated eggs (Fig. 7E).
To test whether polyspermy and the changes of Ca2+ signaling were linked to the alteration of the cortical actin cytoskeleton, we examined the effect of jasplakinolide (JAS), a well characterized agent that stimulates cortical actin polymerization [40].
Fourth, our results supported the hypothesis that BiPN may be linked to the alteration of inflammatory processes.
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These observations clearly show that the adverse effect of fructose on glucose metabolism in the liver is closely linked to the alterations in lipid metabolism.
An incomplete conformational transition in all membrane-associated AP-2 in the clone 1.E cells may also be linked to the alterations in lattice arrangement we see.
The present study results also show that TGFβ transcripts modulate in myopia, which might link to the alterations of ECM production and collagen-degrading enzymes in the sclera of eyes developing myopia.
Remaining defects may result from early exposure of odontoblasts and surrounding osteoblasts to hypophosphatemia, before the commencement of treatment, and/or from intrinsic cell disturbances linked to the genetic alteration(s).
It's unclear whether that episode is linked to the latest alteration to Pornhub's Russia policy — forcing users to log in with their account on the social networking site Vkontakte.
The idea that the heparin-induced polyspermy was linked to the structural alteration of the cortical actin cytoskeleton was strongly supported by the finding that cortical actin hyperpolymerization by JAS also led to polyspermy, as judged by the formation of multiple initiation sites of Ca2+ signals.
The increase in these parameters is linked to the morphological alteration with transition from cocci of the untreated control to elongated cells.
This was a result of an enhanced activation of dendritic cells by BM4, a property directly linked to the structural alteration of the molecule [ 2, 3].
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