Sentence examples for linked to the aggressive from inspiring English sources

Hypoxia-inducible genes have been linked to the aggressive phenotype of cancer.

Nasu et al.'s [ 27] and Sood et al.'s [ 4] study on melanoma cell lines also demonstrated that VM was linked to the aggressive tumor cell phenotype.

Taken together, these data suggest that the increase in tumour lactate and BCAA and decreased PE, only detectable in vivo, could reflect contribution from the tumour microenvironment, while the increase in PCr, aspartate and alanine levels observed in the CALR tumours and 3D spheroids may be linked to the aggressive growth phenotype they exhibit in comparison with their CALS counterpart.

Because a loss of p27 expression has been linked to the aggressive behaviour in a variety of human epithelial tumours including breast cancer, the induction of p27 expression could lead to cell cycle arrest and inhibition of tumour growth (Tan et al, 1997; Lloyd et al, 1999; Macri and Loda, 1999).

It links to the aggressive nature of breast tumours and the long term survival of the patients.

Only 5-105-10percent all breast cancers are linked to the deadly aggressive BRCA 1 and BRCA 2 genes.

Besides, it was shown that the ability to reestablish tumour heterogeneity is not necessarily linked to the more aggressive phenotype.

In spite of reducing cell proliferation rates, tetraploidization has also been linked to the metastatic, aggressive as well as drug resistant stages of certain human malignancies (Castedo et al. 2006; Davoli and de Lange 2011).

Except for that in gastric carcinoma, the PLK mRNA level in these carcinomas was directly linked to the biologically aggressive phenotype of the tumour and/or worse prognosis for the patient (Wolf et al, 1997; Knecht et al, 1999; Tokumitsu et al, 1999).

At R.B.S.'s investment banking hub in Greenwich, Conn., top executives most closely linked to the bank's aggressive expansion into the credit markets are being removed.

Moreover, the de-regulation of this signaling system is linked to the promotion of aggressive and metastatic tumors in humans [2].