Sentence examples for linked to the accumulation from inspiring English sources

The illness has been linked to the accumulation of certain proteins in the brain, but what causes symptoms has been unclear.

Accumulation of septins at the phagocytic cup is thus intimately linked to the accumulation of actin, albeit in an unknown fashion.

Nonetheless, it remains to be investigated whether the upregulated Notch3 expression in PKBα−/− ISP8 cells is functionally linked to the accumulation of DN3 and ISP8 thymocytes and the increased CD25 surface expression among DN3 thymocytes.

Insulin resistance has been linked to the accumulation of intramyocellular lipids in skeletal muscle of diabetic patients [9], [10] in relation with the lipogenic transcription factor SREBP-1c which mediates insulin's actions on hepatic [11], [12], [13] and skeletal muscle gene expression in humans [14] and rodents [15].

Also, it has been suggested that tumour progression is linked to the accumulation of SCA.

The overexpression of BAFF in brain tumors could be linked to the accumulation of tumor cells or to inflammatory signals.

A buffer zone linked to the flow accumulation of 50 m was created in order to include only the susceptible points inside these areas.

This effect might be possibly linked to the K accumulation capacity by the crop, since that the releasement of this nutrient in soil was significantly improved when the composts were applied in conjunction with phonolite (Fig. 3a).

PrPSc accumulation in MLN peaked during the preclinical phase of scrapie, indicating that dysregulated genes that were not common to both disease stages could not be specifically linked to the prion accumulation process.

Thus, it is not surprising that neurodegenerative dementia diseases, which have been linked to the abnormal accumulation of proteins and to alteration of synaptic plasticity, have been associated to the autophagic system [ 41].

Implications and future directions It is well-established that HD progression is linked to the toxic accumulation of mutant huntingtin protein; however, loss of wild-type huntingtin function might also contribute to neuronal cell death.