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Thus, protein synthesis may not only be linked to generation of pMHC I, but could involve novel translational mechanisms.
Furthermore, protein synthesis could be linked to generation of pMHC I in normal uninfected cells as well because the antigen presentation pathway is constitutively active in all cells.
The production of energy in the form of ATP in the 10 enzyme-catalyzed process of glycolysis is linked to generation of intermediates and reducing power in the form of NADH which are subsequently used in biosynthetic pathways.
However, oxidative biotransformation is always linked to generation of reactive intermediates that might lead to cellular injuries.
Deletions of CARD and RING domains in cIAP2 are linked to generation of an oncoprotein in MALT (mucosa-associated lymphoid tissue) lymphoma.
Moreover, β-AR activation, although classically linked to generation of cAMP, has been shown in other studies to influence MAPK activation in a PKA-independent manner [ 18].
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PAs catabolism is tightly linked to ROS generation, because amino oxidases generate hydrogen peroxide (H2O2), which mediates ROS signaling [ 19].
In addition, chronic inflammation has been linked to the generation of local and general patterns of immune suppression that protect tumours from immune recognition and attack [ 40].
Since the oxidation of DHO to orotate is linked to the generation of superoxide from mitochondria [ 24, 25], inhibition of DHODH by siRNA may alter the rate of superoxide generation from mitochondria.
He is a key person in certain networks, so he is linked to that generation.
Such a tariff should emphasize the 'right' moments to use electricity, intuitively linked to renewable generation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com