Sentence examples for linked to cleft from inspiring English sources

Although 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) exposure is linked to cleft palate at a high rate, the mechanism remains to be elucidated.

Finally, our study found that admissions and total length of stay were clearly linked to cleft type classification.

Utilization of a number of sophisticated genetic approaches such as linkage, association and genome-wide association studies have enabled the identification of numerous genes and gene loci that have been linked to orofacial clefting.

The small set of reference samples (30 CEPH trios) of [Western] European descent in HapMap may not be sufficiently representative of the Danish or Norwegian population, especially if common alleles are overrepresented and rare alleles more strongly linked to facial clefting are underrepresented.

AP-2α has also been linked to human orofacial clefting defects via its regulation of target genes, including p63 and IRF6 (Ferretti et al., 2011; Rahimov et al., 2008; Wang et al., 2013).

Mutations in the frequently deleted gene TBX22 are linked to non-syndromic cleft palate [37], but TBX2 has no known role in tumorigenesis.

Post pregnancy low B12 levels and low infant serum folate have also been linked to increased oral cleft risk [ 81].

Systemic corticosteroids are generally considered low risk for teratogenicity, with historical links to cleft palate [ 28, 29] although this association is unclear [ 30].

Regardless of their origin, it appears that many typical TLPs possess an antifungal activity, which is probably linked to a conserved acidic cleft in their 3D structure.

Differences in admissions and total time in hospital for cleft-related care were observed between cleft types, again with the more severe cleft types linked to more admissions and longer duration of hospital stay.

As mTOR has been regarded as a master regulator of protein synthesis (Foster and Fingar, 2010) and AP-1 DNA binding is critical for the transcriptional control of a number of genes (Shaulian, 2010), it is possible that the removal of Glu from the synaptic cleft is linked to gene expression regulation in glia cells.