Sentence examples for linked to alterations of from inspiring English sources
Mood disorders and substance abuse disorders are risk factors for suicide and have also been linked to alterations of DNA methylation in several genes [24], [25], [36], [37].
Several of these risk variants have been linked to alterations of CLU expression and alternative splicing in AD [ 103– 105].
Therefore, further understanding of the underlying mechanisms in this model will help to develop treatments that counteract the adverse cardiac remodeling that is linked to alterations of SRF function in individuals with DCM.
Mutations in one causative candidate gene, EFHC1, have recently been linked to alterations of several neural development steps, including migration, connection formation and apoptosis, the latter potentially leading to maintenance of hyperexcitable neurons (De Nijs et al., 2013).
The modulation of LTB4 production in OA osteoblasts was also linked to alterations of FLAP expression in these cells in response to 1,25(OH)2D3 and TGF-β as observed in other cell systems [ 30, 31, 44, 58].
Many of these methylation changes are also linked to alterations of the SAE transcriptional program, indicating that epigenetic modifications likely play an important role in the pathogenesis of smoking-induced lung disease.
Ground based timber harvesting on wet sites has been linked to alteration of soil properties that may result in reduced long term site productivity.
These effects appear to be linked to alteration of the AKT-signaling pathway.
These cells exhibit telomere dysfunction and chromosomal end-to-end to fusions, specifically linked to alteration of SIRT6 enzymatic activity.
The activity exerted by PgD5 against the phytopathogenic fungi and S. cerevisiae was linked to alteration of fungal membrane permeability.
Then, we determined whether down-regulation of CerS1 transcription is linked to alteration of endogenous Sp1 recruitment to the promoter in UM-SCC-1 cells compared to keratinocytes using quantitative-chromatin immuno-precipitation (Q-ChIP).
