Severe preeclampsia with shallow placentation has also been linked to acquired and inherited maternal thrombophilias and recurrent decidual hemorrhage, which generates thrombin from decidual cell expressed tissue factor.
The Hollywood center was selected by the county as a key site for detecting the antibody, whose presence indicates past exposure to the HTLV-III virus, which has been linked to acquired immune deficiency syndrome, or AIDS.
Moreover, elevated AXL levels have been linked to acquired resistance to EGFR inhibitors in lung cancer [ 7, 8].
Just as there are several sensitizing EGFR mutations that predict response to EGFR TKIs, other mutations have been linked to acquired resistance.
A plethora of potential binding targets has been identified, including cytoskeletal components such as actin and myosin, and proteins linked to acquired neurodegenerative diseases such as synuclein, tau and β-amyloid [4], [17], [18].
Fatty acid synthase (FASN), a key complex catalyzing fatty acid synthesis, is linked to acquired docetaxel/trastuzumab/adriamycin resistance in breast cancer or intrinsic gemcitabine and radiation resistance in pancreatic cancer.
Sensitivity to EGFR inhibition has been linked to acquired mutations in the ATP binding site of the EGFR kinase domain and to increased IGF signaling, Co-inhibition of EGFR and IGF-1R has been found to cause synergy in growth inhibition and apoptosis induction in human breast cancer cells [ 8].
This is the first population-based study on drowning where data from multiple datasets have been linked to acquire the most comprehensive identification of Indigenous status, and to capture as many cases as possible of fatal as well as non-fatal drowning among this age group.
Our previous studies revealed that chronic induction of ARE-dependent genes may be linked to acquired apoptotic resistance and malignant transformation of keratinocytes following iAs3+ exposure, whereas NRF2 has been recognized as a key transcription factor in iAs3+-induced antioxidant response (Pi et al. 2003, 2007, 2008).
The increased proportion of Gb3-expressing cells after cisplatin treatment suggests that cisplatin induces Gb3 expression in cancer cells, that cisplatin preferentially eradicates cell with low Gb3 expression, and that Gb3 expression is linked to acquired-cisplatin resistance.
