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Although these EGF-induced nuclear responses are alike, our PRL-array results here are directly linked to a defined transcription site.
23 Each GEMS site is linked to a defined population under a demographic surveillance system (DSS) that captures census data 2 3 times per year.
Sorting gate refinement using index sorting can be applied to any population that can be linked to a defined single-cell functional assay.
An important unanswered question is whether H. pylori strains having a particular CagA structure could be linked to a defined gastroduodenal disease.
Eleven of the 56 genes have not been linked to a defined cellular or physiological process since they comprise recently identified genes for which GO terms were inferred from electronic annotation.
Induction of MAP kinase pathways was shown to contribute to specific toxic responses to Cr VI) (Wakeman et al. 2005; Wang and Shi 2001), although in other cases could not be linked to a defined end point of Cr VI) toxicity (Ceryak et al. 2004; Chuang and Yang 2001).
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But some of the matches could not be linked to a clearly defined biological function, and therefore these metabolites were considered unidentified.
Some case/control studies were linked to a large defined population that had undergone a detailed recent census or that was under prospective demographic surveillance so that population-wide incidence rates could potentially be calculated; some cohort studies were also nested within such defined populations to allow potential extrapolations of incidence to the larger population.
Total RNA extracts were treated with DNase I (DNA-free, Ambion, Austin, TX, USA) and cDNA generated by using the Superscript II system (Invitrogen) for reverse transcription primed by random octamers that were linked to an arbitrary defined 17-mer primer sequence[15].
RNA (0.5 μg) from the frontal cortex biopsy specimen was treated with DNase I (Ambion DNA- free; Austin, TX, USA) and reverse transcribed by using Superscript II (Invitrogen, Carlsbad, CA, USA) with random octamer primers linked to an arbitrary defined 17-mer primer sequence (Eurofins MWG Operon, Huntsville, AL, USA).
To do so, we abstracted from the GVKBIO databases 11,827 patents which are linked to a GPCR target with a defined Entrez Gene ID (as November 2010).
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