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Other researchers propose some model matching and database linked methods, such as fingerprinting algorithm, which are always time-consuming [12].
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At the higher selection coefficients, the linked method separated driver and passenger loci almost perfectly.
This result arises because the linked method can detect hitchhiking of neutral alleles with drivers.
Examination of selection coefficients inferred with the linked method showed an improvement in two characteristics.
The accuracy of the linked method showed dramatic changes with increased time between sampling points, dts.
At each level of selection, the accuracy of the linked method was greater than that of the unlinked method.
In general, a good fit was observed between the frequencies inferred with the linked method and the observed allele frequencies.
We used an integrated qualitative approach to data collection and a linked method approach to data analysis [ 26].
In systems for which every locus was a driver, improved selection coefficients were observed with the linked method compared to the unlinked method.
First, driver loci inferred using the linked method had substantially more accurate (higher) selection coefficients than those obtained with the unlinked method.
Second, passenger loci at which a fixation occurred were inferred to have significantly lower selection coefficients under the linked method compared to the unlinked method.
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