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Upper panel : the approach within each data set with initial selection of the 80%% most variable genes, and subsequent generation of linked matrices of gene correlation values and associated p values.
We provided a method of probing 3D structure in its native form over time and linking matrix dynamics with cellular organization and function using graph theory.
Our results closely link matrix catabolism with decreased LKB1 and AMPK activities, present in OA, aging, and injured chondrocytes.
In knee OA, disease progression is linked to matrix degradation and loss of molecules.
This can reduce the biases linked to matrix type components (inhibitors) often observed with qPCR.
TGF β is amongst the most well-studied signaling molecule in wound healing and is particularly linked to matrix and collagen production during wound healing.
Potential stem cell treatments are also substantially affected by material mechanical properties since their lineage-specific differentiation has been repeatedly linked to matrix stiffness.
Invasive behaviour in breast cancer cell lines has been linked to matrix metalloproteinases (MMPs), so we also determined if PKD1 regulates the expression and activity of these enzymes.
We used the data of flights and passenger capacities to set up an airport-link matrix and a passenger-capacity matrix.
The degrees of belief are stored in a storage-efficient manner in a data structure called a canonical link matrix [17].
However, the regression coefficient for order was much smaller than those for the master matrix and of the in- minus out-link matrix (0.08 as compared with 0.26 and 0.20, respectively).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com