And then there was the couple who linked fingers..
Two strategies have been described that allow the productive assembly of more than three canonically linked fingers on a DNA site: connecting sets of fingers using linkers (covalent), or assembling sets of fingers using dimerization domains (non-covalent).
Because the 3-D keys are in close contact with the fingers, the user may unintentionally press undesired keys because intentional movements of one finger are accompanied by unintentional movements of linked fingers.
The data show that tight junctions and adherens junctions, which were both present and linking unwounded epidermal cells, were lost between the loosening basal cells, whereas desmosomal junctions were retained and it was these that provided the local bonds that linked finger-like protrusions between neighboring, migrating epidermal cells.
Moving some fingers individually is difficult because some finger muscles and corticospinal neurons are linked between fingers, and the amount of finger linkage can vary from person to person [15].
Here we demonstrate efficient site-specific recombination at several sequences taken from a 1.9 kilobasepair locus of biotechnological interest (in the bovine β-casein gene), mediated by zinc finger recombinases (ZFRs), chimaeric enzymes with linked zinc finger (DNA recognition) and recombinase (catalytic) domains.
Moving some fingers individually is difficult because the finger muscles and corticospinal neurons are linked between fingers [15].
In addition, arrays of linked Zif268 finger-variants allow binding of longer asymmetric sequences [14], [15].
This gene family includes four linked zinc-finger transcription factors: odd, brother of odd with entrails limited (bowl), sister of odd and bowl (sob), and drumstick (drm).
Holding burning cigarettes between fingers is linked with yellow fingers.
From this screen TRIAD1 (two RING [really interesting new gene] fingers and DRIL [double RING finger linked] 1) emerged as being required for the degradation of both growth hormone (GH) and epidermal growth factor (EGF).
