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We then wanted to determine if promoter homology was associated with the linked expression of the two proto-oncogene clusters.
This variable but linked expression was also observed in four different breast carcinoma cell lines tested (Fig. 3B).
Interestingly, we detected linked expression of NKp30L and NKp44L on many cell lines derived from solid tumors.
This is unlikely to be an artifact or a cross-reactivity of our staining reagents as we did not find such linked expression on cells of hematopoietic origin.
IL-8 is also mitogenic [13], angiogenic [14] and, through linked expression of MMP's, influences tumour cell motility such that invasion is enhanced [15].
LD linked expression data to physiological drought effects.
Transcripts are shown on the top or bottom of the schematic to reflect linked expression.
Immunohistochemistry of breast tumors demonstrated linked expression of PPAR-γ and p27 [ 17, 47].
11, 12 In addition, several small studies have linked expression of individual miRNAs to outcomes in esophageal adenocarcinoma.
Second, while the expression of hY1, hY3 and hY4 RNAs are to some extent linked, expression of hY5 RNA and Ki67 mRNA appear largely separate.
The basis for this interallelic crosstalk remains unclear, although it is reminiscent of the linked expression of alleles described in plants and flies (Hollick, 2012; Kassis, 2012).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com