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We then wanted to determine if promoter homology was associated with the linked expression of the two proto-oncogene clusters.
This variable but linked expression was also observed in four different breast carcinoma cell lines tested (Fig. 3B).
Interestingly, we detected linked expression of NKp30L and NKp44L on many cell lines derived from solid tumors.
This is unlikely to be an artifact or a cross-reactivity of our staining reagents as we did not find such linked expression on cells of hematopoietic origin.
IL-8 is also mitogenic [13], angiogenic [14] and, through linked expression of MMP's, influences tumour cell motility such that invasion is enhanced [15].
To initially assess the antigen specificity and expression of the 1.9 TCR, we transduced Jurkat T cells and observed efficient and linked expression of the 1.9 TCR and eGFP (Figure 1B).
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Pessia et al. (2012) analyzed protein protein interactions of X-linked human genes and found that levels of autosomal and X-linked expression were similar for genes encoding components of large complexes, thereby being considered dosage sensitive.
Male-to-female Z-linked expression was compared, and MWU was employed to test for significant differences between the sexes Z-linked expression within each quartile.
All tissues except antennae showed a significant interaction between sex and Z-linked expression, with greater male Z-linked expression (table 2).
Notably, no reduction in male Z-linked expression relative to autosomes was reported for P. interpuctella.
Some other papers examined induction-linked expression in a limited number of genes only.
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