Masamha, C.P. et al. CFIm25 links alternative polyadenylation to glioblastoma tumour suppression.
According to the Encyclopedia of American Gospel Music, "Jesus Freak" is believed to be one of the first songs to link alternative rock and rap rock in CCM.
First mechanistic insights into MYC-driven splice site usage were provided by linking alternative splicing of the Raf kinase to differential MYC expression (Rauch et al, 2011).
However, our finding that these were disproportionately NOVA-mediated actions to maintain neuronal transcript levels (215 vs 14) is consistent with an overall action linking alternative splicing suppression of NMD exons to steady-state transcript levels.
Also, CTCF induced RNA polymerase II pausing was shown to link alternative mRNA splicing to DNA methylation at a CTCF binding site in genomic DNA encoding an intron [ 3].
AtSKIP functions as not only a positive regulator and putative potential transcription factor in the abiotic stress signaling pathway in Arabidopsis [ 23], but also a component of the spliceosome linking alternative splicing and the circadian clock in Arabidopsis [ 24].
Recently our group was able to link alternative splicing regulation to EC tumor biology and clinical outcome [ 14] and identified HNRNPG and HTRA2-BETA1 as independent prognosticators for EC type I progression-free survival.
The procedure has been implemented in Delphi and linked to Alternative Transients Program ATP.
Interestingly, the presence of Sin3a is reported as an epigenetic feature linked to alternative mRNA splicing.
A-to-I editing of pre-mRNA by ADAR proteins in a few cases has previously been linked to alternative expression of transcript isoforms.
Differences in fruit fly foraging behavior are linked to alternative alleles that result in changes in abundance of foraging mRNA and protein kinase activity [ 15].
