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In our alternative approach, we used oligonucleotides that have blocks of DMED (dimethylethylenediamine -modified internucleosidimethylethylenediamine -modified-ends that stabinternucleosidenuclinkagesanearlso have a series of atheirst five phosphodiester linkages to direct targeted RNaseH-mediated degradation of endogenous mRNA (Dagle et al., 2000).
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Intuitively, we assume that linkages to directed neighbors with the same function class with the target protein of interest typically have triangle structures (see Figure 1(b)).
More recently, it has also been established that barley CSLH genes, like CSLF, are able to direct mixed-linkage β-glucan biosynthesis [ 21].
Elsewhere, however, and in Europe in particular, agencies often have less direct linkages to elected assemblies.
Again, since all DSSTox substances and associated structure content have been deposited in PubChem, direct linkages to PubChem content are available through PubChem identifiers (CIDs).
Current conservation practice recommendations could be improved by incorporating more direct linkages to the ecologically based technical literature, more up-to-date information on adaptive management strategies in highly variable rangeland systems, and integration of monitoring strategies designed to directly test the efficacy of specific conservation practices.
These diseases have direct linkages to a lack of exercise and poor diet and diets higher in total calories, processed sugars and unhealthy fats but low in fiber.
When the information can be spatio-temporally mapped it reveals relationships and logics that have also quantifiable and direct linkages to the urban and built environment at multiple scales.
Historically, most research conducted by the NIEHS community has emphasized an assessment of the toxicologic effects of environmental agents on biological processes using animal models; in many instances these studies have not made direct linkages to human disease.
Calculated human concentrations can be integrated with toxicity data such as tissue concentrations, providing direct linkages to high throughput toxicity test data for screening-level risk assessment (Judson et al. 2011).
Amino acids are then joined via peptide linkages to assemble specific proteins, as directed by the genetic material and in response to the body's needs at the time.
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