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Drug loading, physiochemical properties and pH lability of the DOX-hydrazone linkage were evaluated in vitro.
The polarity and configuration of the cyclization linkage were implicated important in assuming the active conformation.
The surface cracks were tortuous, typical crack branching and linkage were observed.
They considered that the transmission efficiency of the triangular belt, the gearbox and the four-bar linkage were 3, 4 and 3%, respectively (Brown 1980).
Collagen mimetic polypeptides (CMPs) pendanted with linear or dendritic oligoethylene glycols (OEG) via ether linkage were synthesized, and their thermoresponsiveness, secondary structures and supramolecular assembly investigated.
Novel, selective M2 muscarinic antagonists, which replace the metabolically labile styrenyl moiety of the prototypical M2 antagonist 1 with an ether linkage, were synthesized.
Acid-resistant heavy fluorous tags, in which all three fluorous chains are tethered in a symmetric manner by carbon carbon linkage, were designed and synthesized from ethyl crotonate.
A series of phenylene-linked iridium bis-pyridine-2-sulfonamide (bpsa) complexes substituted with electron-donating and electron-withdrawing groups and a new bpsa complex containing naphthalene linkage were synthesized and investigated as efficient and robust water oxidation catalysts.
Novel addition curable phenolic resins bearing terminal ethynyl groups anchored to benzene ring through a phenyl azo linkage were realized by the coupling reaction between novolac and 3-ethynyl phenyl diazonium salt.
In opposite no signal of linkage were obtained in 5q31q33 or 6p (MHC) region.
Regions of linkage were identified by binning neighboring markers and counting linked markers within the bins.
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