Sentence examples for linkage test from inspiring English sources

The significance was determined empirically, by running the linkage test on ten permuted datasets.

We planned a linkage test of the PTPN22- 1858T allele RA hypothesis, restricted to RF+ RA patients.

The remaining loci were dissected into groups at increasing stringency levels of the linkage test (LOD values from 3 to 12).

Effect sizes for the SNPs analysed using single-marker linkage test were nearly 2-fold higher than effects identified using multi-SNP models (average R = 3.8%).

We searched for QTL linked to these metaphenotypes by applying a non-parametric linkage test at every marker position, as previously described [ 58].

One of the most interesting findings in genetic studies of ED comes from a genome wide linkage test by Grice and colleagues in 2002 [ 60].

In order to estimate these quantities, we must compare the number of statistically significant linkage tests with the estimated number of truly null and truly alternative linkage tests.

Thus, approximately 103 true-positive trans-acting QTL are detected in the 5067 random single marker linkage tests.

There were 157 linkages called significant at LOD≥1.37 among the 5067 random marker linkage tests, and the associated FDR was ≈0.342.

For the 1206 linkage tests significant at LOD≥1.37, the FDR estimated by Storey's and Tibshirani's method was 0.026.

First, we estimated the proportion of truly null tests (denoted π0) and truly alternative tests (1−π0) across all 5067 single marker linkage tests performed at the marker closest to the locus of the gene in question.