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Two series of compounds were designed and synthesized by conjugating coumarin at 3-position with benzimidazole at 2-position through a single bond (series 4) as well as an amide linkage (series 5).
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With the availability of a high-density molecular linkage map, a series of RHLs with overlapping heterozygous segments in the target region (we denote such a series as stepwise RHLs) could be selected from a segregating population derived from the original RHL.
The amounts of linkage between a series of genes can be combined to form a linear linkage map that roughly describes the arrangement of the genes along the chromosome.
'600' series linkage keys use assessment date.
Following the assessment of linkage accuracy, a series of automated and semi-automated procedures were used on the patient based record groups to identify and resolve errors.
In several reactions a new product was observed in the reaction mixture, using thin-layer chromatography, which was not observed after work-up and chromatography, suggesting that an ester linkage in this series of compounds may be unstable.
We recently described the pharmacological activities of a set of chimeric compounds, (R)- D, similar to (R)- 1 and (R)- 4–(R)- 10, in which a single bond separated the two terminal aromatic rings, rather than the oxymethylene (OCH2) linkage in the series described herein.
This capability depends on the optional linkage to time-series input files that enables VP to simulate mixing zone and far-field parameters for long periods.
The imide linkages in this series displayed keto-iminol tautomerism, since they showed O H stretching bands 3634 3617 cm−1 and additional O H stretching bands in compound 5d at 3495 cm−1 and N H stretching bands 3164 3141 cm−1.
To fully investigate the linkage effect of a series of small molecules, two reference compounds BDCTBT and BDETBT were also studied systematically, consisting of 2-phenylacrylonitrile and styrene as π-linkage, respectively.
In recent years, rice scientists conducted a series of linkage analyses using several biparental mapping populations to identify the quantitative trait loci (QTLs) associated with tolerance to flooding during anaerobic germination.
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