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The strongest linkage result for any of the seven elements was for Pb on chromosome 3, as previously reported (Whitfield et al. 2007).
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Moreover, linkage results for camptothecin-induced cytotoxicity were replicated across multiple datasets.
Moreover, it is the first study to report replication of linkage results for drug-induced cytotoxicity using this model.
This is the first study to report replication of linkage results for drug-induced cytotoxicity using the CEPH cell lines.
The linkage results for individual chromosomes are provided in Figure 1 in Supplement 1.
Figure 1 shows the linkage results for asthma, total IgE and all other subgroups.
Supplementary Figures 1- 4 display genome-wide linkage results for all chromosomes according to study center and all centers combined.
The genome-wide linkage results for the seven traits are illustrated in Figure 1 with the strongest linkage signals for each trait listed in Table 3.
Positive linkage results for these highly rearranged chromosomes in the deer mouse would have been a strong indicator of Mus homology.
Linkage results for SPT and RAST for HDM were quite similar, but the HDM SPT positive group – which is a smaller group-, reached the suggestive linkage level on chromosome 12.
Previously, we reported linkage results for the categorical diagnosis of autism (defined in a broad and narrow way) using 1181 families from the Autism Genome Project (AGP) Consortium data (3).
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