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Initial localization of disease-related loci has traditionally been performed using family-based linkage methods to scan the genome.
The ISD used established probabilistic linkage methods to link the females in our cohort to records in the SMR 2 database.
We performed the hierarchical clustering using Ward's method [ 27] as well as the single, average and complete linkage methods to obtain a hierarchical clustering of the 25 pathways.
WADLS uses probabilistic data linkage methods to create and maintain a dynamic set of linkages across 30 administrative health datasets, including public and private hospital morbidity data, pharmaceutical claims records and death data [ 26].
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A hierarchical cluster analysis was conducted on the total sample with between-group linkage method to identify a men group with an adequate preventive attitude.
We used Euclidian distance and Ward's linkage method to perform the clustering (JMP 6.0 software, SAS Institute, Cary, NC, USA).
Agglomerative hierarchical clustering was applied using the complete linkage method to investigate whether there was evidence for natural groupings of tumor samples based on correlations between gene-expression profiles.
We used a probabilistic record linkage method to match employee records with the anonymous death certificates.
Cluster software [ 78] was used to perform hierarchical clustering analysis using Euclidean Distance and average linkage method to create probe sets and sample trees.
Then, we employed the record linkage method to normalize drugs and targets to the unique identifiers by utilizing the public data sources including PubChem, Entrez Gene, and UniProt.
We employ a probabilistic record linkage method to combine incidence data and the official mortality data for Tyrol collected by Statistics Austria.
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