The "unlinked" reference dataset was composed of epidemiologically unlinked sequences using a dataset composed of sequences from individuals with no known epidemiologic linkage, including sequences from the HIVDB and from previously adjudicated "unlinked" pairs from this study cohort.
LINKDATAGEN 17 produced files for linkage, including removing Mendelian errors.
Thus, non-stratified analyses (which did not require linkage) include 597 participants; stratified analyses (which required linkage) include 595 participants.
Variables that will be used for record linkage include full name, address and date of birth.
Common encoding algorithms used in record linkage include Soundex [ 21], NYSIIS [ 22] and Metaphone [ 23].
Matching: Contains the classes that are involved in the record linkage, including preprocessing of incoming fields.
Results from OSA identified multiple genomic regions showing increased evidence for linkage, including regions on chromosomes 1 and 22 which implicated several biological candidates for disease [ 14].
Both the linkage (including both parents) and association populations were arranged in a randomized complete block design with three replications (except F2 individuals).
Results from OSA identified multiple genomic regions showing increased evidence for linkage, including regions on chromosomes 22 and 1 which implicated several strong biological candidates for disease [ 14].
