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They provide the vital linkage evidence of crimes occurring on the ground".
Third, in the presence of linkage evidence, we offer a means to estimate the location of the disease locus along with its sampling uncertainty.
Affected individuals in the demographically ancient isolate of ethnic Dargins (No. 6022) who suffered from disorganized schizophrenia showed the highest linkage evidence at 17p11 p12 (LOD = 3.73), while isolates with a predominant aggregation of paranoid schizophrenia (Nos. 6005, 6011, and 6034) showed the highest linkage evidence at 22q11 (LOD = 3.0 and 4.4).
The risk of these spurious associations can be alleviated when incorporating prior linkage evidence into the analysis.
Under a rare or private functional variant model with extensive locus heterogeneity, linkage evidence will (by definition) be modest and generally inconsistent [4], [5]).
We have presented statistically significant linkage evidence for a potential CHD susceptibility locus on chromosome 14 in a South Indian population selected for consanguinity.
Similar(18)
The association and linkage evidences provided by the present study remain nevertheless statistically modest, suggesting at most a minor RA susceptibility marker.
This highlights the importance of "bottom up" strengthening of the linkage between evidence and policy, particularly in the African Region.
These alternate linkages were evidence of recombination among minicircles.
Quantitative-trait linkage analysis produced evidence of significant linkage on chromosome 5q21 and suggestive linkage on chromosomes 8, 10, and 13.
This linkage is further evidence that compliance with AHRQ stroke guidelines may be a valid quality of care indicator.
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