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Estimates of local effective population size by the linkage disequilibrium method were very large or infinite in most localities within the Western part of the sampled range (Mississippi and Louisiana) suggesting current population density is high in that region.
According to the linkage disequilibrium method, the decrease was 98% in Lokoué and 95% in Lossi.
According to confidence interval estimated with both the Bayesian method and the linkage disequilibrium method, Ne ranged from 10 to 80 for the Lossi population and 10 to 1,000 for the Lokoué population.
In particular, the linkage disequilibrium method is more restrictive because it assumes selective neutrality, unlinked markers and a closed population, and its sensitivity to population decline has not been tested.
As in the linkage disequilibrium method, this method has the advantage that only a single cohort sample is required.
The linkage disequilibrium method is based on the fact that genetic drift generates nonrandom association among alleles in different loci.
Similar(31)
Single- and multiple-QTL analyses using combined linkage and linkage disequilibrium methods were performed.
Recently, linkage disequilibrium methods based on unrelated individuals have been advocated as powerful tools to refine estimates of gene location.
We investigate the current genetic structure of natural populations of C. japonica using several thousand SNPs and characterize the outlier loci using linkage mapping and linkage disequilibrium methods.
To estimate N e, we used the single sample linkage disequilibrium methods implemented in the program ldne (Waples and Do 2008).
For instance, for two closely positioned QTL on the same chromosome, classical linkage-based analysis will show a large QTL signal around one location, whereas linkage disequilibrium methods may indicate two separate narrow signals.
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