Exact(9)
Linked data users need to consider what information is required to properly assess linkage bias.
After elimination of linkage bias, a normal distribution of t-statistics was observed.
Even if a linkage bias by education is present, it is rather unlikely that it will change over time.
These results convinced most of the scientists that much of the observed overdominance was probably pseudo-overdominance due to linkage bias (Lamkey and Edwards 1999).
For practical considerations, we recommend using cancer death as an endpoint with careful review of the death records to minimize sticky-diagnosis and slippery linkage bias.
Although the data did not allow us to check for a potential linkage bias by education, 8 we assumed that our results are not affected for several reasons: first, our main interest is the development in mortality differentials over time.
Similar(51)
Rdp1 is not in our synthetic sick table (Table S2) because of the data processing to eliminate linkage biases.
Such 'slippery-linkage' bias might arise from complications during the diagnostic process or following specific therapeutic interventions for screen-detected disease (such as complications following surgery for the screen-detected cancer).
To evaluate the potential effects of linkage on bias and sampling variance, I created a simple linkage model.
Overly restrictive linkage parameters biased the incidence proportion downwards by 43% and the HR by as much as 27% for some factors.
Clearly, out-of-state emigration likely varies from state to state which could lead to differences in the impact of the non-linkage assumption bias.
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Justyna Jupowicz-Kozak
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