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Of the 276 small molecules in the M-P link map for lung cancer, only one (0.36%) molecule had degree eight, and 19671.0.0%) molecules had degree one.
Another instance is the separate subnetwork shaded by light slate blue in the M-P link map for lung cancer from GSE5364).
Another example of an sM-sP link is between isoniazid and the glutathione metabolism pathway in the link map for liver cancer from GSE5364).
A third example of an sM-sP link is between alsterpaullone and the insulin signaling pathway in the link map for lung cancer from GSE5364).
The M-P link map for breast cancer and its degree distribution are shown in Figure 2. The heatmap for M-P link map of breast cancer is shown in Figure 4(a).
Of the 263 small molecules in the M-P link map for liver cancer, only one (0.38%) molecule had the highest degree eight, and 183 (69.6%) molecules had degree one.
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M-P link maps for these three cancers from GSE5364 were constructed.
Cross-link map for PRC2 in complex with AEBP2.
The M-P link maps and degree distributions for liver and lung cancers are shown in Figures S1 and S2, respectively (see Figures S1 and S2 in Supplementary Material available online at http://dx.doi.org/10.1155/2014/931825).org/10.1155/2014/931825
Each of the four algorithms consists of three steps: node mapping, link mapping and definition of paths for transfer of the required images.
The pseudo code for mapping of incoming requests using Bin packing is shown in Algorithm 1. Greedy node mapping combined with a K-shortest path algorithm for the link mapping phase (Multi-Site) [18].
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Justyna Jupowicz-Kozak
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