Apart from identifying salty wells and salty and/or hard water locations, elders in Mtumba and Mahoma Nyika were able to link concentration of water salinity with seasons.
It has been suggested that age-related deterioration in trabecular microarchitecture and changes in collagen cross-link concentrations may contribute to skeletal fragility.
Cross-link concentrations were expressed relative to collagen content determined by colorimetric measurement of hydroxyproline in the original hydrolysate.
In addition to the cross-linker structure (and stiffness), cross-linking proteins in most cases only bind transiently to binding sites and differing cross-link concentrations lead to various larger-scale architectures (Section 2.1.7).
Interestingly, the alterations in divalent and trivalent cross-link concentrations were disproportionate; thus there were significant increases in the PYD/DHLNL ratio in the treated animals compared to corresponding controls whereas the treatment effects on HLNL were much less marked than for DHLNL.
The discrepancy in the magnitude of change between the biochemically- and spectroscopically-determined ratio is most likely due to the fact that as we have previously reported the relationship between biologically- and spectroscopically-determined cross-link concentrations of Pyd is not a linear one [33].
At the very least, risk assessors could estimate changes in population-weighted concentrations of air toxics, even in the absence of appropriate concentration response functions linking concentrations with health end points.
We linked concentrations of PFAAs measured in enrolled pregnant women with their daughters' serum concentrations of total testosterone and SHBG measured at 15 years of age using data from two separate investigations previously conducted on the ALSPAC.
There was a significant positive correlation between the hydroxylysyl pyridinoline (PYD) cross-link concentration and fillet firmness, where PYD explained 28% of the total variation.
In data evaluation, this was taken into account by combing the relevant congeners of Penta-, Octand anDeca-BDEDE, respectively, thus linking concentration trends in herring gull eggs to commercial products (Figures 6 and 7). Figure 6 Penta-BDE in herring gull eggs from three ESB locations in German coastal waters.
