Sentence examples for lines that demonstrate from inspiring English sources

We report here the presence of a rare population of uPAR-positive cells in human SCLC cell lines that demonstrate significant drug resistance to traditional chemotherapeutic agents such as 5-fluorouracil (5-FU), cisplatin and etoposide.

Gene expression data derived from cell lines that demonstrate differential sensitivity to EGFR TKI, such as erlotinib, were used to generate models for a priori prediction of response.

It remains to be determined whether lines that demonstrate rapid courtship onset also display specific deficits in discriminating appropriate courtship targets.

Speculation has begun as to how the cells survive with partial mitochondrial function due to the lack of Complex I [ 25]; the bioenergetic consequences are minimal in T. cruzi strains with compromised maxicircle genes [ 26], consistent with survival of experimentally compromised T. brucei lines that demonstrate Complex I participation in electron transport [ 27].

Our data show that PI3K/AKT inhibition in these pancreatic cancer cells results in a decrease in BCL-2 and an increase in BAX without effect on other members of the BCL-2 family; furthermore, this effect appears limited to those cell lines that demonstrate AKT activation under basal conditions.

The NIH Developmental Therapeutics Program has determined that Bcl-xL may play a unique role in the general resistance of cancer cells to cytotoxic agents by showing that a variety of cancer cell lines that demonstrate resistance to 70,000 cytotoxic agents are characterized by high Bcl-xL expression [ 26].

This is the first study using the CEPH cell lines that demonstrates that a specific pattern of QTLs could be established for a class of drugs which share a mechanism of action.

In the SCLC cell lines that demonstrated GIRK1 mRNA expression, we also saw GIRK1 protein expression.

Stable lines that demonstrated a significant rescue of Swip after reserpine treatment were kept for further analysis.

High levels of I κB α were detected in all drug-resistant cancer cell lines that demonstrated high nuclear NF- κB activity.

All colorectal cancer cell lines that demonstrated methylation of the CDH13 promoter lacked CDH13 gene expression, while CDH13 was expressed in the oesophageal cancer cell line with unmethylation of the CDH13.