Sentence examples for linear trapezoidal method from inspiring English sources

According to FDA guidelines for generic drugs studies, the area under the curve (AUC) was calculated using a linear trapezoidal method, by applying non-compartmental data analysis.

According to FDA guidelines, for generic drugs studies, the area under the curve (AUC) was calculated by the Linear Trapezoidal method, by applying, non-compartmental data analysis using the PK Solver 2.0 software (as an Excel add-on).

Area under the concentration time curve to the time point measured at 48hr after the first dose (AUC0 48h) was calculated with the linear trapezoidal method.

The AUC was calculated by the linear trapezoidal method.

The AUC0− t was estimated using the linear trapezoidal method.

AUCtau was determined using the linear trapezoidal method.

AUC0-t was estimated by a combination of linear trapezoidal methods on increasing concentrations and logarithmic trapezoidal methods on decreasing concentrations.

This program uses a log-linear trapezoidal method for determining the AUC values.

The area under the concentration time curve extrapolated to infinity (AUC0−∞) was calculated by the log-linear trapezoidal method for the observed values, with extrapolation to infinity including at least three points on the terminal phase.

Individual plasma concentration profiles of irinotecan and its catabolites were fitted according to a two-compartment open model by means of the WinNonlin 5.1 computer software (Pharsight Corporation, Mountain View, CA, USA) The AUC of irinotecan (CPT-11), SN-38 and SN-38glu from 0 to 63.25 days was calculated by the log-linear trapezoidal method until the last sampling time.

The AUClast was computed using the linear trapezoidal approximation method.