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The motif order was rearranged in DRM sequences to match the linear organization of canonical DNMTs.
The linear organization of collagen fibers in tendons results in optimal stiffness and strength at low strains under tensile load.
A company like Abercrombie & Fitch, for example, which has huge marketing disciplines, huge real estate disciplines, huge supply chain disciplines, one of the hallmark of these commerce business is that they can have much linear organization with people focusing on a narrower set of things that are critical to the businesses and making the business really go.
In the same context, we address the apparent discrepancy between the spatial distribution of transcriptionally active sites in the nucleus and our understanding of the linear organization of genes on the linear genome.
We demonstrate here that the microtubule cytoskeleton gradually transitions from a radial to linear organization during neurulation and that microtubules function in conjunction with the polarity protein Pard3 to mediate centrosome positioning.
Beyond the linear organization of genes and transcripts on chromosomes lies a more complex (and still poorly understood) network of chromosome loops and twists through which promoters and more distal elements, such as enhancers, can communicate their regulatory information to each other.
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Whereas linear organizations are necessarily constrained by limited resources, exponential organizations are governed by an assumption of abundance.
It doesn't seem to matter what arguments you give, such as "linear organizations in an exponential world"—your phrase that I really like.
This model reveals 1) a multifractal regionalization where many regions coexist that are far from equilibrium and 2) this non-linear organization has significant molecular and medical genetic implications for understanding the role of Alu elements in genome stability and structure of the human genome.
Multicellular skin substitutes containing PVA borate networks display a linear cellular organization, reduced cellularity and the formation of a keratinized epidermis that resembles normal skin.
The C2 domain packs closely on top of the Notch-binding DSL domain without altering the structure of the DSL-EGF1-3 pofthen of the construct in comparison with our earlier structure for this region in isolation, and therefore extends the near-linear domain organization (Cordle et al., 2008a).
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