Sentence examples for linear linkages with from inspiring English sources

Apart from being a substrate of linear ubiquitination, NEMO was shown to bind linear linkages with 100-fold higher affinity than K63-linkages through its UBAN domain 41, 136, 137, suggesting that LUBAC, once recruited, orchestrates the sequence of events by enabling recruitment of NEMO via linear linkages on TNF RSC I components, like RIP1 and possibly others.

Glutathione along with tocopherols were in linear linkage with antioxidant capacity, while inverse association with that of oxidative damage.

Glycogen is a complex branched polymer of glucose, with α- 1,4) linear linkages and α- 1,4) branching lineares and a broad distribution of molinkagesweights, ∼10–10 Dand

Having established FAM105B as a Met1-linkage-specific OTU DUB, we named the enzyme OTULIN (OTU DUB with linear linkage specificity).

For detection of linear-specific ubiquitination of RIP1 within the necrosome, the immunoprecipitated endogenous caspase-8 complexes were washed in lysis buffer and then disrupted in 6 M urea containing buffer and reimmunoprecipitated with linear linkage-specific anti-ubiquitin antibody as described previously.

His dissertation established the principle of the linear linkage of genes in heredity.

A crystal structure of the linear-linkage-specific antibody Fab fragment in complex with linear diubiquitin provides molecular insight into the nature of linear chain specificity.

This demonstrated that necrosome-associated RIP1 is modified with linear polyubiquitin linkages.

The purified curdlan was a linear polysaccharide composed of exclusively β- 1,3 -glucosidic linkages with the molecular weight of 160,000 Da by GPC.

Taken together, these results indicate that RIP1 is the primary target of necroptotic ubiquitination, predominantly with K63 and linear chain linkages.

Meanwhile, the Tgs of poly(3)–poly(5) bearing linear siloxane linkages were much lower (−115 to −23 °C), and decreased with increasing length of the siloxane linkages.