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And for intercalating amyloid-beta oligomerization, long and linear conformation with a lipophilic group was considered.
Although PQcOx-biT demonstrates a linear conformation, its electron distribution of both the ground and excited-states are localized on the acceptor unit.
Since the absence of an internal isopeptide bond from the D181A substitution lacked any impact on pilus polymerization (Supplementary Fig. 1), this suggests that internal K D isopeptide bond formation occurs when the N-domain takes on the linear conformation after the intermolecular K T isopeptide bond is produced.
In the presence of excess hydrogen bond donors and acceptors, the oligoanthranilamide strand retained its linear conformation, pointing to the potential of this modular design as a useful and stable scaffold for molecular recognition studies.
However, PQcOx-TT exhibits a linear conformation with a dihedral angle under 7° and shows crystallized domains and oriented morphology with shoulder peaks in the UV vis spectra of both solution and film states.
However, when the nanoprobe hybridizes with the target DNA, the stem-loop structure denatures and is converted to the linear conformation.
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These results point out that wrapped conformations are dynamically less favored in solution than linear conformations.
2) The authors use the angular reconstitution approach to calculate 3D structures for the complex in extended and linear conformations using tilted images.
The RIIα linker regions were modeled as unstructured polypeptides connecting the sub-domains of the AKAP18γ-PKA holoenzyme complex oriented in the triangular and linear conformations determined by EM.
The complexes exhibit octahedral geometry and Pt ligand bond lengths are similar to those of reported related complexes, 5, 6, 9 with the nitrogen atoms of the azido ligands adopting almost linear conformations (∢Nα-Nβ-Nγ ∼174 175°).
Non-linear conformations of crystal-bound peptides have also been predicted for a lithostatine undecapeptide adsorbed to calcite [73] and a dentin matrix protein-1 peptide adsorbed to HA [36].
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