Sentence examples similar to lineage propensity from inspiring English sources
With C' we ensure that a function exists which relates lineage propensities to a tissue fate.
With C' we ensure that a function exists with which we can aggregate lineage propensities into a tissue fate.
In both cases, the profile of lineage propensities is assumed given, and a set of fates is reduced (and for C' the tissue fates stay the same).
The derivation of the relation of tissue fates as an aggregation (consensus) of individual lineage propensities is without consideration for the mechanisms of how the propensities for individual stem cell lineages arise.
For the hematopoietic system, Glauche et al. [ 12] developed a stochastic model of lineage specification as a progressive restriction of lineage potential due to a competition between different interacting lineage propensities.
Similar, IIA is concerned with what happens to the ranking of tissue propensities when the set of actually considered fates being given, the profile of lineage propensities changes somehow.
The condition for consistency is concerned with what happens to the ranking of tissue propensities when the profile of lineage propensities being given, the set of actually considered fates changes in a certain way.
If such potential-but-not-actual fates do exist, the analysis should be independent of who they are and of what the lineages' propensity rankings over them are.
An intuitive example of a cross-level principle is the majority rule: the fate of the tissue corresponds to the one with the greatest number of first places in the lineages propensity rankings.
IIA means that the analysis of rankings among the actually considered fates should be robust in the sense that ranking of tissue fates and the lineages' propensity rankings over the actually considered fates should be the same if propensities over potential-but-not-considered candidate fates change.
The next function of the ESCAPE web interface is a tool to predict lineage-propensity differentiation outcome on single or combinatorial KD of multiple pluripotency factors.
